Rev Esp Enferm Dig. 2024 Sep 5. doi: 10.17235/reed.2024.10697/2024. Online ahead of print.

Gema Marset ¹, Samuel Fornos ², Etna Masip ², María Ángeles Calzado ³, Begoña Polo ⁴, María Roca ⁵, Carmen Ribes ⁶, Ester Donat ⁷

Author information

¹Pediatric Gastroenterology and Hepatology, Hospital Universitari i Politécnic La Fe, Spain.

²Pediatric Gastroenterology and Hepatology, Hospital Universitari i Politécnic La Fe.

³Pediatric Gastroenterology and Hepatology, Exploring histological remission in pediatric patients with celiac disease.

⁴Pediatric Gastroenterology and Hepatology, Exploring histological remission in pediatric patients with celiac disease, Valencia.

⁵Celiac Disease and Digestive Immunopathology, Instituto de Investigación Sanitaria La Fe.

⁶Celiac Disease and Digestive Immunology, Instituto de Investigación Sanitaria La Fe.

⁷Pediatric Gastroenterology and Hepatology, Hospital Universitari i Politécnic La Fe, España,.

Abstract

In response to the article presented by Laura Rodríguez-Martínez et al., which discusses mucosal healing rates in celiac disease and the risk factors for persistent damage despite a gluten-free diet in adults, we present a review of biopsies from pediatric patients with celiac disease performed at our center between 2001 and 2020. Notably, there is a higher rate of mucosal healing compared to adults (83%), and factors such as age at diagnosis, histological involvement, and anti-tissue transglutaminase antibody levels at diagnosis do not appear to be significant risk factors, unlike in adults.